Research Pipeline


Mild Traumatic Brain Injury (mTBI), commonly known as concussion is the most common brain injury, inflicting a tremendous cost burden on the healthcare system, estimated at approximately $17 Billion annually in the US alone.

One of the common causes for concussion is sports related injury. Sport-Related Concussion (SRC) affects as many as 3.8 million people in the US alone. The injury is often not directly visible, and early mTBI symptoms may appear mild, but they can lead to significant, life-long impairment in an individual’s ability to function physically, cognitively, and psychologically. It is therefore highly important that SRC is promptly assessed and managed to prevent further complications.

Given the great variability in symptoms and presentations, the clinical diagnosis of concussion is particularly difficult, and represents a significant challenge for sports medicine providers. Moreover, once a concussion is diagnosed, determining when the patient is clear to return to full activity represents an even bigger challenge for clinicians, since it is well known today that symptoms resolution alone does not necessarily reflect complete recovery. Despite ongoing research, there is no single, direct, objective and sensitive test available for concussion management.   Current recommendations are that sports medicine providers apply a multifaceted concussion assessment battery that combines subjective symptoms, motor control (e.g., postural stability), and cognitive assessment.  Neuroimaging techniques play only a limited role in concussion assessment, either due to the functional (i.e. non-structural) nature of the injury (in the case of CT, MRI, DTI) or as a result of their cost and availability.

BNA has been used in multiple studies that have demonstrated the value of having an additional objective layer of information and how assessing similarity to RBNM may be used in the clinical context of concussion and mild TBI.  The company’s BNA™ platform has attracted some of  the  top  research  centers  for  traumatic  brain  injury  in  the  U.S. to  serve  as  clinical  sites  for  the advancement of the technology in this area.




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