“…Another Israeli brain technology company looking to improve depression treatment effectiveness is Elminda, which was recently awarded EUR 2.8M by the European Commission to bring its technology to European patients suffering from depression. Elminda’s brain analytics product, BNA-PREDICT, predicts responsiveness to both antidepressants and neurostimulation treatments, allowing physicians to not only select the most effective anti-depression treatment but also monitor that treatment’s effect directly in the brain of the patients. “We are very proud of the two-year award granted to Elminda by the European Commission’s prestigious Horizon 2020’s phase 2 Small and Medium-sized Enterprise (SME) instrument”, says Dr. Roni Sharon, Elminda’s Harvard-trained Medical Director.
March 10th, 2019
Read the whole paper on Transnational sports medicine: “Sleep correlates of brain network activation and clinical measures in youth American football players“.
March 7th, 2019
elminda and RI.Group to Form RI.Mind – a Joint Venture to Apply elminda’s Brain Analytics Technology for Personalization of Medical Cannabis.
The future of cannabis health lies in personalization
elminda Ltd., a leading brain technology company, and RI.Group Investment Management Ltd., a strategic investor in the fields of agriculture, healthcare and natural resources have teamed up to utilize proven technology to address one of the main challenges of medical cannabis health – personalization.
RI.Mind will focus on changing the way cannabis is being consumed by providing growers, doctors, and pharmaceutical developers with the tools and data to predict, identify, prescribe and optimize the most appropriate medical cannabis drug for each patient.
Currently, there are over 1,000 strains of cannabis being actively cultivated, all with widely different cannabinoid ratios and terpene profiles, capable of inducing different subjective experiences and medical therapeutic effects. Finding the right strain for a particular patient dealing with a specific condition can be a challenge. Another key factor in personalizing cannabis care relates to dosing. How much should a patient take to maximize the effectiveness of the treatment while minimizing side effects.
The legal cannabis market is slated to hit $75 billion by 2030, and with this amount of growth comes responsibility.
Industry leaders should feel empowered and motivated to develop or adopt personalized healthcare within the cannabis space. The medical power of cannabis is undeniable and as the market continues to evolve and professionalize, RI.Mind will strive to make this medicine accessible and effective to the largest patient community possible.
Selecting the right cannabis product for the treatment of brain related disorders presents an enormous challenge for doctors where the success rate is less than 50%. elminda’s brain analytics product, the BNA™, was developed to help physicians select the most effective treatment and monitor its effect in the brain for patients suffering from brain related disorders.
“We are excited by the new partnership created between elminda and RI.Group and believe that RI.Mind’s vision will change the way medical cannabis is consumed,” said Roy Bercovitz, Managing Partner at RI.Group. “The opportunity to create objective empirical data of the effects of cannabis on cognitive conditions is critical to personalized medicine,” said Ronen Gadot, CEO of elminda. “We think that by focusing on the medical effects of cannabis, we target the most critical point of the cannabis supply chain,” said Gal Skalsky, Managing Partner at RI.Group.
Multi Million Euro Award by European Commission Will Support Deployment of elminda’s ‘BNA-PREDICT’ to Improve Depression Treatment Effectiveness
Herzliya, Israel – elminda Ltd, a leading brain technology company, was awarded by the European Commission multi-million € to bring its breakthrough technology to European patients suffering from depression. Over 50 million Europeans are suffering from depression, a devastating disease with significant social and financial impact on the European community. Depression is the number one cause of disability and accounts for more than 30% of the total cost associated with brain related diseases. Depression is one of the only diseases with increasing mortality rates.
Selecting the right treatment for depressive patients presents an enormous challenge for doctors and success rate is less than 50%. elminda’s brain analytics product, the BNA-PREDICT, was developed to predict responsiveness to both antidepressants and neurostimulation treatments and help physicians select the most effective anti-depressant treatment and monitor treatment effect directly in the brain for patients suffering from depression. The use of BNA-PREDICT increases treatment effectiveness, reduces healthcare costs as well as reduces mortality from the disease.
The two-year award was granted to elminda through the prestigious Horizon 2020’s phase 2 Small and Medium-sized Enterprise (SME) instrument, which targets ground breaking innovations that have the potential to profoundly impact the EU economy and global healthcare. Phase 2 requests had a success rate of 3.6%.
The award will be used to solidify further development of elminda’s BNA-PREDICT technology and product, as well as to deploy a multi-center clinical study focused on optimization of anti-depressant treatment decisions for patients suffering from depression. The clinical study will be conducted in collaboration with leading research and clinical centers in Israel, Germany, Switzerland and Italy.
“We are excited by the continued vote of confidence of the European Commission,” said Ronen Gadot, CEO of elminda. “This award will allow us to strengthen our collaboration with clinical key opinion leaders and industry partners, with the goal of further solidifying the clinical utility and cost effectiveness of BNA-PREDICT in improving the practice in the treatment of mental disorders”.
February 4th, 2019
Dr. Ziv Peremen, the vice-president of medical solutions at elminda Ltd., discusses the unique features of its cutting-edge solution for brain-related disorders, the Brain Network Analytics System (BNA). Read More on Health Europa Magazine.
November 27th, 2018
A strategic agreement for the introduction of Brain Checkup program was signed between elminda and iKang Guobin, the second leading health operator in China. The agreement was signed during Chinese Vice President Wang Qishan visit to Israel during which elminda’s Brain Network Analytics technology was presented to VP Wang as one of Israel’s leading technologies.
Mrs. Zhou Yafang, a Senior Vice President of the iKang Guobin Group and Dean of the Shanghai Guobin Medical Center, signed the commercial strategic agreement with elminda, for their brain checkup program. Zhou had participated as a leading entrepreneur at the Israeli Innovation Summit.
The brain checkup program will complement Guobin medical Center’s current offering of health and wellness annual checkups, a 20 year long operation which Mrs. Zhou Yafang, founded and expanded throughout China.
elminda & iKang teams at the Israeli Innovation Summit
Mrs. Zhou Yafang at the Israeli Innovation Summit
The Villages Health and elminda joint Study Receives Erickson Foundation Award for Excellence in Aging Research at 2018 APHA Annual Meeting
November 1st, 2018
elminda is pleased to announce that a manuscript, entitled “Evaluating Brain Health: Early Findings on the Utility of a Novel Technology to Access Brain Health in Late Life,” will receive the prestigious Erickson Foundation Award for Excellence in Aging Research at the upcoming 2018 American Public Health Association (“APHA”) annual meeting being held November 9-17 in San Diego, California.
The award-winning manuscript highlights the results of a study to evaluate the capability and potential of BNA to reliably assess cognitive function in older adults, distinguish normal cognitive decline from the early stages of abnormal disease process, and detect cognitive deterioration over time. In the study, the potential for utilizing BNA assessment for early detection of brain disorders, such as Alzheimer’s Disease (“AD”) and Mild Cognitive Impairment, and for characterizing significant differentiation between healthy aging brains and those experiencing adverse outcomes, was shown. Implications for future research, policy and practice were also discussed.
The study reflects a unique collaboration between corporate-community and academic partners that is vital to robustly demonstrating the BNA’s real-world utility.
“We are deeply honored that the APHA Aging & Public Health Section and the Section Award Committee have recognized The Villages Health and elminda joint research with this award,” said Ronen Gadot, Chief Executive Officer of elminda. “As awareness and acceptance of BNA among clinicians and researchers continues to grow, we believe it has the potential to become the go-to analysis tool to diagnose and early detect brain functional problems, as well as a standardize way to measure the impact of therapeutic intervention on brain disorders.”
Read more on BioTuesdays
Elminda BNA Technology, one of five breakthrough Innovations Presented to Chinese Vice President, Mr. Wang Qishan in his visit to Israel
October 25th, 2018
Chinese Vice President Wang Qishan arrived in Israel Monday, October 22 for a four-day official visit focusing on high-level talks on economic cooperation and innovation as part of Prime Minister Netanyahu Innovation Summit.
At day three of his visit Vice President Wang was introduced up-close and personal to five Israeli transformational innovations selected by the Prime Minister office and the Israel Innovation Authority expert panel. Elminda’s Brain Network Analytics (BNA™) was one of the five selected innovations and one of two in healthcare.
The BNA™ brain analytics platform technology harnesses advanced data science and artificial intelligence to unlock brain function for early detection of brain problems and personalization of specific treatments.
“We are thrilled that elminda was chosen for this unique showcase to Vice President Wang Qishan and Prime Minister Netanyahu” said Ronen Gadot elminda’s, who demonstrated the technology. Elminda has been taking a comprehensive approach to understanding brain health with the world largest database of brain functional information and commercial products that can allow, for the first time, the detection of early signs of memory problems, evaluation of mental health & depression more objectively and quickly assess the effect of various treatments on the brain. Mr. Gadot also informed VP Wang of the first strategic partnership that Elminda is establishing in China in the private and public sectors to address some of the major health challenges associated with the growing aging population.
September 18th, 2018
Closely-held elminda’s Brain Networks Analytics (BNA) technology is going beyond genetics, imaging and behavioral tests to unlock brain functioning and how the brain changes over time, combining Big Data and AI-driven analytics in a single technology platform. Read more on BIOTUESDAYS
We are proud to announce that elminda’s paper: “Improved Back-projection Cortical Potential Imaging by Multi-Resolution Optimization Technique” has been accepted and published in Brain Topography journal.
Inside Florida’s largest retirement community researchers using BNA technology are trying to peel back the secrets of the brain
May 16th, 2018
April 25th, 2018
elminda was selected to be part of a delegation of companies led by the Innovation Authority, which will represent Israel at the national pavilion of Israel at the world’s leading exhibition BIO Boston on June 2018.
elminda was selected to be part of the Exhibition of Contemporary Israeli Innovation, at the Peres Center for Peace and Innovation
April 25th, 2018
elminda is honored to be selected to be part of the Exhibition of Contemporary Israeli Innovation, at the Peres Center for Peace and Innovation. The official opening will take place on October 2018.
The committee, which included a variety of professionals, in cooperation with the Ministry of Economics and the Innovation Authority, reviewed hundreds of submissions by companies, including many breakthroughs and inventions and found elminda to be suitable to represent the contemporary Israeli innovation
June 20th, 2017
Ronen Gadot, CEO of elminda and Robert Kraft, New England Patriots chairman and CEO
May 29th, 2017
elminda Ltd. is delighted to announce the appointment of Dr. Arun Menawat as the new Chairman of its Board.
Dr. Arun Menawat, has an accomplished history of executive leadership success in the healthcare industry. He served as the President & CEO and Chairman of the Board of Novadaq Technologies Inc. from April 2003 to July 2016, where he led the company from a start-up to among the top ten fasted growing medical device companies. Dr. Menawat led the company to an IPO in the Canadian TSX and US NASDAQ listing.
Previously, he served as President and Chief Operating Officer at Cedara Software, medical imaging software company (Now part of IBM) where he led the company to profitability. The company was sold to Merge Healthcare and ultimately to IBM for their Watson program. Before joining Cedara Software, Dr. Menawat held senior management positions at Tenneco Inc. and Hercules Inc.
Dr. Arun Menawat obtained a Ph.D. in Chemical (Bio) Engineering from the University of Maryland, while concurrently completing a fellowship in biomedical engineering at the U.S. National Institute of Health, and holds an Executive MBA from the J.L. Kellogg School of Management, Northwestern University. In 2014, Dr. Menawat was named the EY Ontario Entrepreneur of the Year in the health sciences category
elminda would like to convey its appreciation to Prof. Amir Geva. His leadership, talent and expertise have been a great asset to the Company in his time as Chairman and we are pleased to have his continued involvement as a board member and as the CTO of the Company.
elminda was selected as one of the most innovative companies to accompany Prime Minister Benjamin Netanyahu during his formal visit to China
March 23rd, 2017
This week, Prime Minister Benjamin Netanyahu visited China and was accompanied by a senior business delegation of dozens of Israeli businesspeople from the various industries and companies active in China, as well as from companies interested in penetrating the Chinese market. Delegation members attended a business forum with over 500 invited guests, that was chaired by the Prime Minister. Among the companies that were carefully selected to showcase Israel’s most transformational innovations was elminda.
The visit followed an invitation by Chinese President Xi Jinping and marked 25 years since the establishment of diplomatic relations between the two countries. During this visit, Israel and China signed cooperation agreements in aviation, education, bringing Chinese construction workers to Israel, science, health, environmental protection and a multi-year plan for a task force on strengthening bilateral economic ties
“We will continue the talks on establishing a free trade agreement between China and Israel and we will hold the third joint Israel-China innovation conference. Of course, we are continuing to develop new markets and to open new markets for the Israeli economy. I expect all ministers to cooperate on this, and they are doing so”, said Mr. Netanyahu.
October 6th, 2016
‘Study Utilizing elminda’s BNA™ Awarded the International Clinical Scholar Award at American College of Sports Medicine Annual Meeting
June 3rd, 2016
Briana Scurry, Olympian, World Cup U.S. Women’s Soccer Player and member of the BNA Sports Advisory Board discusses the importance of new brain health technologies during Brain Health Awareness Week 2016
March 17th, 2016
Link to video: Personal Journeys with Brain Injury: Briana Scurry
March 16th, 2016
The research presented will examine a novel approach utilizing BNA to assess sports concussion through electrophysiological network activity which underlies brain function and dysfunction.
March 2nd, 2016
elminda to Present at the Eleventh World Congress on Brain Injury: BNA™ As a Physiological Marker for Sports-Related Concussion
March 2nd, 2016
February 4th, 2016
Link to video: USA Today
February 4th, 2016
November 16th, 2015
BNA™ (Brain Network Analytics) provides detailed knowledge of brain function over time. Potential to impact an estimated 2 billion people worldwide living with neurological, psychiatric disorders.
CHICAGO, November 16, 2015 – elminda Ltd., a pioneer in neuroscience-based technology for analyzing brain network functionality, today announced the successful completion of an oversubscribed $28 million Series C financing round. The global syndicate of investors in this round includes Shanda Group, New England Patriots owner – The Kraft Group, Wexford Capital, WR Hambrecht & Co, Palisade Capital Management, OurCrowd and Healthcrest AG and others. Proceeds will be used to continue advancement of elminda’s proprietary BNA™ (Brain Network Analytics) system, which uses multi-channel EEG-ERP electrophysiology technology to provide a more accurate, objective assessment of brain functionality over time. elminda will also use the funds for commercial and clinical adoption following BNA’s 2014 FDA clearance in the U.S., and CE Mark approval in Europe for brain function assessment.
“We are thrilled to have attracted such a strong group of new and existing investors,” said Ronen Gadot, chief executive officer of elminda. “This support is a testament to the vast potential of BNA technology to advance our understanding of how the brain works, and to positively impact people’s lives. We plan to bring BNA to the forefront as a significant resource to monitor and manage the health of your brain throughout the course of your life.”
“As an investor who has followed the advancements of the company for several years, we look forward to supporting elminda as it further unlocks the potential of BNA to be the preeminent market leader by offering an objective platform for brain function assessment and management of brain disorders,” said Robert Kraft of the Kraft Group.
BNA is a non-invasive technology for measuring and analyzing brain function. It uses advanced signal processing and machine-learning algorithms of big populations’ data in order to identify patterns of neuronal networks activated during a specific brain function, such as memory or attention. The information can then be utilized for personalized clinical decision making. It has the potential to impact an estimated two billion people worldwide living with neurological and psychiatric disorders, such as Alzheimer’s disease, Parkinson’s disease, depression, and ADHD, as well as those who have sustained traumatic brain injuries, like concussion. BNA is responsive to the BRAIN Initiative announced by the White House, which focuses on revolutionizing our understanding of human brain function through the development and application of innovative technologies.
“elminda has developed a truly disruptive technology that addresses a crucial unmet need,” said Tianqiao Chen of Shanda Group. “We’re excited to help develop and promote such a unique technology that can potentially catalyze new treatment options for those affected by brain dysfunction.”
“BNA’s exploration of brain function has already affected the lives of young people and their physicians in the U.S. seeking additional guidance for critical brain health decisions,” said Bill Hambrecht of WR Hambrecht & Co. “It has the potential to be of value to each and every one of us in our lifetime.”
BNA is currently available to healthcare providers at 15 locations in eight U.S. cities, including Chicago, Los Angeles, Philadelphia, Minneapolis, Phoenix, Ann Arbor, Hartford, and Palm Beach.
BNA™ is a breakthrough technology to monitor and manage the health of your brain throughout the course of your life. It combines non-invasive, multi-channel EEG technology with sophisticated signal processing and analysis algorithms to measure patterns of brain networks activated during specific brain processes to deliver meaningful insights into brain functionality. In addition to concussion, use of BNA is being explored as a tool for physicians to monitor change in brain networks to help identify disease onset and assess treatment efficacy for a broad range of previously elusive conditions such as depression, pain, or memory loss. The BNA Analysis System is to be used by qualified medical professionals for the post-hoc analysis of the human Electroencephalogram (EEG), utilizing evoked response potentials (ERP). The device is indicated in the U.S. for use in individuals 14 to 24 years of age with the Auditory Oddball task only. For more information about BNA visit, www.elminda.com.
About elminda Ltd.
elminda was founded in 2006 by Professor Amir Geva to address an unmet need to objectively assess brain health and brain-related disorders in order to enhance diagnosis and treatment across a full spectrum of neurological and psychological disorders. elminda translates state-of-the-art neuroscience via advanced algorithmic science into clinically meaningful Brain Network Analytics (BNA™) maps. elminda is a preferred partner of industry-leading organizations based on the rigor of its science and technology development. elminda was recognized on Fast Company’s 2015 list of the World’s Most Innovative Companies, and was named a 2015 World Economic Forum Technology Pioneer.
September 3rd, 2015
In honor of the famous neurologist’s life, GEEKTIME has compiled a list of five of the most innovative brain tech companies and projects operating today. read more.
August 5th, 2015
elminda has been honored among a select group of global innovators named to the World Economic Forum’s Technology Pioneers for 2015. The World Economic Forum’s Technology Pioneers program recognizes companies from around the world that are involved in the design, development and deployment of new technologies, and are poised to have a significant impact on business and society. Read more on Yahoo finance, ISRAEL21c and WEF press release. Read WEF interview with CEO Ronen Gadot.
June 30th, 2015
A study published by Brain Imaging and Behavior provides important new information about the assessment of patients following a concussion, particularly those with post-traumatic migraine (PTM). The study compared individuals with PTM following sport-related concussion (SRC) to those without PTM following SRC, as well as healthy individuals, utilizing Brain Network Analytics (BNA™). The findings indicate that individuals with PTM following sports-related concussion exhibit reduced BNA network activity and connectivity scores, and support use of BNA in assessing PTM throughout post-concussion recovery. The full study can be accessed here.
June 9th, 2015
April 12th, 2015
Herzliya – elminda Ltd. announced today that the Israeli Ministry of Health has approved registration of the company’s BNA™ Analysis System as a medical device for the assessment of brain function. Brain Network Activity (BNA™) combines non-invasive, multi-channel EEG technology with sophisticated signal processing and analysis algorithms to measure patterns of brain networks activated during specific brain processes and deliver both quantitative and qualitative insights into brain functionality. The BNA™ output allows healthcare providers to assess a patient’s functional brain network activity and compare it with functional network activity of healthy brains. BNA™ is currently cleared for 14 to 24 year-olds, and the company is conducting additional research activities to further expand the indicated age group.
elminda Ranked Among Fast Company Top 50 Most Innovative Companies Worldwide and Top 10 Most Innovative Healthcare and Israel Lists
February 9th, 2015
elminda, creator of the ground-breaking Brain Network Analytics (BNA™) technology has been recognized once again for its innovative approach to neuroscience and management of brain disorders. The company was included on Fast Company’s annual list of the World’s Most Innovative Companies that ranks the top 50 companies that are radically changing an industry, consumer habits and assumptions. Not only was elminda honored on the Top 50 Worldwide list, but it also placed within the Top 10 Most Innovative companies in the Healthcare and Israel categories.
In August 2014, elminda announced that BNA™ was cleared by the U.S. Food and Drug Administration (FDA) for the analysis of brain functional network activity, initially indicated for 14 to 24 year olds. elminda research showed, for the first time, the ability of BNA to map pain pathways in the brain and objectively and sensitively differentiate between a drug effect and a placebo effect on the brain – previously only possible by subjective measures.
The full list of companies is in the March 2015 issue of Fast Company, and more information can be found here.
January 22nd, 2015
LONDON (Alliance News) – Electrical Geodesics Inc on Thursday said it has signed a two-year deal with elminda to provide its GES 400 systems to the US-Israeli company’s Brain Network Analytics platform.
The BNA platform is an analysis system which received clearance from the US Food and Drug Administration last year for the assessment of brain function in 14-to-24-year-olds.
Under the deal, Electrical Geodesics will supply and support customers of elminda who buy the BNA analysis system with its GES 400 dense array EEG systems on pre-determined terms. It did not provide financial details of the deal.
“We have worked with elminda over a number of years and are pleased that their research efforts have led to the BNA system receiving FDA clearance. elminda recognises the need for the precision dense array EEG provides to enable objective assessment of brain disorders and injuries,” said Electrical Geodesics Chief Executive Officer Don Tucker.
See more on Morningstar
December 22nd, 2014
Watch IBA News story on BNA™ broadcast on November 26th 2014
September 28th, 2014
BNA™ FDA clearance in the news:
MDBR Medical Device Business Review, August 5th, 2014
Globes, August 6th, 2014
Times of Israel, August 13th, 2014
Israel 21C, August 14th, 2014
Jewish Business News, August 26th, 2014
August 27th, 2014
ANN ARBOR, Michigan; “Concussion test that feels like ‘octopus giving your head a hug’ could greatly benefit NFL players, other athletes”. Read the full story on BNATM
August 4th, 2014
Advanced brain analysis and mapping technology enables assessment of brain health based on objective neurophysiological measures
CHICAGO, Aug. 4, 2014 – elminda Ltd. announced today that the United States Food and Drug Administration (FDA) has cleared the company’s BNA™ Analysis System for the assessment of brain function. Brain Network Activity (BNA™) combines non-invasive, multi-channel EEG technology with sophisticated signal processing and analysis algorithms to measure patterns of brain networks activated during specific brain processes and deliver both quantitative and qualitative insights into brain functionality. The BNA™ output allows healthcare providers to assess a patient’s functional brain network activity and compare it with functional network activity of healthy brains. BNA™ is currently cleared for 14 to 24 year-olds, and the company is conducting additional research activities to further expand the indicated age group.
“Greater understanding of how our brain processes information, how it gets its job done, ultimately holds the potential to improve brain health and disease management over a person’s lifetime,” said Ronen Gadot, CEO of elminda. “BNA™ adds an objective layer of information to clinical symptom assessments and neurocognitive tests, providing clinicians with a comprehensive view of brain health.”
“BNA™ allows physicians to assess brain health using objective neurological measurements,” said Jeffrey S. Kutcher, M.D., associate professor of neurology, University of Michigan Medical School. “This will allow those of us caring for patients the ability to more clearly differentiate a healthy brain from one affected by disease or injury, and potentially have more informed discussions about lifestyle, activity, prevention and treatment decisions as a result.”
elminda has established a growing database of brain activity from both healthy subjects and patients with brain-related disorders. The database currently includes more than 7,000 BNA™ datasets, which provide a robust, clinically supported foundation to potentially help identify and manage neurological disorders such as ADHD or pain, and brain injuries such as concussion. Prominent clinical institutions across the country are leading research studies focused on the use of BNA™ across several of these areas.
About elminda Ltd.
Founded in 2006 to address an unmet need in the accurate, objective diagnosis and treatment of brain-related disorders, elminda is pioneering brain assessment technologies designed to inform critical decisions by providing a clear view of brain function over time. The company uses a data-driven approach to transform algorithmic science and neuroscience expertise into routine clinical practice, and is a preferred partner of industry-leading organizations based on the rigor of its science and technology development.
BNA™ FDA clearance on the news:
MDBR Medical Devise Business Review, August 5th 2014
Globes, Agust 6th 2014
Times of Israel, August 13th 2014
Israel 21C, August 14th 2014
Jewish Business News, August 26th 2014
June 24th, 2014
Watch the Télématin FR2 story on BNA™ broadcast on June 17th 2014.
March 30th, 2014
elminda has received a certification for EN ISO 13485:2012 and CMDCAS ISO 13485:2003, an international standard for a company-wide quality management system.
March 16th, 2014
Pittsburgh March 12th 2014
UPMC, Israeli company partner on brain-mapping work. A collaboration between the Israeli company elminda, and the UPMC Sports Medicine Concussion Program, has generated research results that could lead to better concussion assessments and more effective treatments. Read the full story on BNA™.
November 21st, 2013
MINNEAPOLIS (WCCO) — This fall, 150 Minnesota youth hockey players are taking part in a study that’s using BNATM, a new concussion test to measure brainwaves. The studies’ directors believe the test could someday give parents an immediate diagnosis and peace of mind. Watch the CBS Minnesota story on BNATM.
elminda and Purdue Pharma L.P. Enter Research Agreement to Develop Novel Diagnostics to Improve Pain Management
January 29th, 2013
elminda and Purdue Pharma L.P. Enter Research Agreement to Develop Novel Diagnostics to Improve Pain Management
Collaboration Extends Use of elminda BNA™ Technology Research
Herzliya, Israel and Stamford, Conn. USA – January 29, 2013 – elminda – the developer of an innovative technology capable of providing drug developers with superior insights into the effect of therapeutic interventions on brain function – has entered into a strategic, multi-year research collaboration agreement with Purdue Pharma L.P., a leading developer of pharmacologic therapies to treat and manage pain.
The staged research collaboration will focus on pain diagnosis and management, through the development of objective assessments of analgesia as well as other subjective responses to treatment, and include several projects aimed at the discovery and development of new clinical diagnostic tests and biomarkers to manage pain and to enable the development of more effective pain treatments.
“We are extremely pleased to enter into this collaboration with Purdue Pharma that will apply our advanced Brain Networks Activation (BNA™) technology to research efforts for the development of better diagnostic tools and biomarkers for pain management,” said Ronen Gadot, CEO of elminda. “Partnering with Purdue Pharma is another significant step forward for elminda, marking an expansion of the company’s collaborations with pharma companies and the addition of pain management to the Company’s portfolio of therapeutic focus.”
elminda’s BNA™ technology combines the most advanced brain imaging tools with elminda’s proprietary algorithms and signal processing to produce unparalleled detail and precision of brain functional mapping. In the area of drug development, the BNA™ technology can shed light on the dynamic functional changes in brain networks pre- and post-drug administration to reveal mechanisms of action, optimize drug dosages and identify responders and non-responders to therapies early in the drug development process.
As part of an expanding R&D innovation strategy, Purdue is broadening the scope of its research collaborations beyond drug discovery and development in order to identify opportunities that can enhance the overall quality of pain management. Purdue scientists are evaluating potential mapping systems to objectively assess pain, new applications and technologies for pain management, new technologies for controlling drug release, and methods to assess treatment compliance.
“We are very excited about this collaboration and look forward to leveraging elminda’s BNA™ technology in a combined effort to enhance the diagnosis, treatment and management of pain. This collaboration is another important effort towards advancing care for pain patients and further demonstrates Purdue’s commitment as a leader in the field of pain management,” said Dr. Craig Landau, Chief Medical Officer for Purdue.
Clinical diagnostic tests to improve pain management and biomarkers for drug development resulting from the collaboration will be used and commercialized by elminda and/or Purdue.
About elminda: elminda was founded in 2006 with the vision of revolutionizing the management of brain disorders and injuries by transforming state-of-the-art neuroscience into bed-side clinical practice, opening a new window into functionality of the brain. The company seeks to dramatically improve clinical decision-making for Central Nervous System (CNS) disease management through wide utilization of its BNA™ testing as an objective measurement of brain function, dysfunction, disease progression and recovery. The elminda BNA™ technology is currently being used for drug development research with leading pharmaceutical companies and in research with prominent academic research centers throughout the U.S. and Europe. In 2012,elminda submitted the technology for FDA clearance. The technology is not currently cleared for clinical use.
About Purdue Pharma L.P: Purdue Pharma and its associated U.S. companies are privately-held pharmaceutical companies known for pioneering research on persistent pain. Headquartered in Stamford, CT, Purdue Pharma is engaged in the research, development, production, and distribution of both prescription and over-the-counter medicine and hospital products. Additional information about Purdue can be found at www.purduepharma.com.
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For Purdue Pharma L.P.
Senior Director, Public Affairs
Purdue Pharma L.P.
February 5th, 2012
The Wonders of our Mind
Receiving a Transmission from the Brain
elminda is developing a tool that measures our brain’s electrical fields and signals during brain activity, in order to enable brain-disorder diagnosis and treatment in real time
One of the most important discoveries in neuroscience – perhaps the final frontier for medical science specifically and for science in general – is the degree to which the brain works as a synchronized, organized system rather than as isolated regions. Another no less important discovery is that the brain is largely flexible and plastic, a fact that gives much hope in regard to its healing abilities. And yet, compared to most fields of modern medicine, such as cardiology, orthopedics and gynecology, in which diagnosis, treatment and follow-up all rely on precise measuring equipment (ultrasound, CT, etc.), the fields of medicine dealing with the brain – such as psychiatry and neurology – are forced to operate under vague, uncertain conditions in terms of the quality of diagnosis and the efficacy of care.
What is it: The goal of the research conducted by Professor Amir Geva over the last thirty years, and by the elminda Corporation, over the last six years, was to bring modern medicine to the brain by developing an imaging and treatment tool that would enable measuring and tracking of the network activities of high neural processes such as memory and identification, clear presentation of the information to the attending physician and, when necessary, repairing and improvement of neural network processes using external or internal stimulus adjusted to measurement. This may improve the lives of one third of the world’s population who suffer from various brain-related illnesses.
It has been known for some time that the brain is composed of complex networks of neurons that work together in time and space to perform complex tasks, such as processing and identifying sensory input, long- and short-term memory storage, attention, and abstract thinking, but it is very difficult to measure this activity.
How does it work: The company’s technology is based on measuring the electrical fields that are created through the brain’s neural electrical activity on the scalp and around the head during the performance of various cognitive tasks, and then reevaluating the relevant active neural network in terms of time and location in the brain, using advanced methods of signal processing and pattern recognition taken from engineering and computer science research.
The brain behind it: Professor Geva, together with Goded Shahaf and Ronen Gadot, set up ElMinda in 2006, with the purpose of measuring network activities of the functional and dysfunctional human brain during performance of various cognitive tasks, to enable diagnosis and treatment of brain disorders while tracking changes in the network activity accordingly.
Status: The company is currently involved in various stages of the complex and expensive process of developing drugs with leading teams from the largest pharmaceutical corporations in the world. The goal of this process is to measure and understand the effects of the drugs on the human brain’s network activities, and thus to develop new and effective drugs whose effects on the human brain are known and measured and which could be used to treat disorders such as Parkinson’s, Alzheimer’s, ADHD, schizophrenia, pain, depression and more. The company is concurrently working to develop a system for the diagnosis and the post-treatment clinical follow-up of various brain disorders and illnesses, including ADHD, concussions, pain, rehabilitation after stroke, and more: this will enable correct decisions to be made based on direct measurement of the activity in the organ being treated – the brain.
January 20th, 2012
Results of a study demonstrating the applicability of BNA™ in ADHD were published in the February 2012 issue of Clinical Neurophysiology.
January 17th, 2012
Introducing a novel approach of network oriented analysis of ERPs, demonstrated on adult attention deficit hyperactivity disorder; G. Shahaf, A. Reches, N. Pinchuk, T. Fisher G. Ben Bashat, A. Kanter, I. Tauber, D. Kerem, I. Laufer, J. Aharon-Peretz, H. Pratt, A.B. Geva.